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Essay 03

AI's biggest impact is in R&D, not apps

The popular story about AI is about software getting smarter. Better assistants, better copilots, better consumer products. That story is real, but it is also the smaller half of what is happening. The larger, slower, and more valuable shift is AI moving into the hard, research-heavy parts of the economy, drug discovery, materials science, defense, energy, and industrial R&D. That is where the deepest value will be created over the next decade, and it changes what kind of leadership these companies need.

Why R&D is the bigger prize

Software has always been fast and cheap to iterate. The constraint there was rarely the cost of an experiment, because shipping a change and measuring it costs almost nothing. In research-heavy industries, the constraint is exactly that. A new molecule, a new material, a new physical system can take years and enormous capital to design, synthesise and test. The cost of a single experiment is high, and the cost of a wrong direction pursued for two years is enormous.

When AI compresses the cost of generating and screening hypotheses in those domains, it does not just make an existing process a little faster. It changes what is economically possible to attempt. Problems that were too expensive to explore become tractable. The space of things worth trying expands. This is a different and larger kind of impact than making a familiar software workflow more convenient, and it is why the most consequential AI work increasingly happens at the boundary between machine learning and a hard science, rather than purely inside software. The market has noticed. AI in drug discovery alone was worth roughly 1.7 billion dollars in 2024 and is projected to reach about 8.5 billion by 2030, a compound annual growth rate above 30 percent, and some platforms already report cutting synthetic and experimental effort by 70 to 80 percent.

The leadership problem this creates

Hiring for these companies is harder than hiring for a pure software team, because the leaders have to live in two worlds at once. A research leader in drug discovery needs genuine command of the biology and genuine command of modern machine learning, plus the judgment to know where the two genuinely combine and where they only appear to. That intersection is narrow. The pool of people who are credible to both a research community and a product organisation is small, and it does not map onto conventional hiring channels, because the best of these people are usually embedded inside research groups, national labs, or specialised companies rather than circulating in the open market.

It also requires leaders who can manage long time horizons without losing momentum. Software leadership is often optimised for speed of iteration and a quarterly rhythm. Research leadership has to hold a direction through cycles that do not pay off quickly, while still shipping enough to keep the business funded and the team motivated. Those are different instincts, and confusing the two is a common and costly hiring mistake. A leader imported from a fast-iteration software culture can grow impatient with the very timelines that define the science, and a pure researcher can lose the company by never connecting the work to something shippable.

What good looks like

The leaders who thrive in AI-led R&D share a few traits. They translate between science and engineering fluently, so a research insight can become a system and a system can inform the next research question, closing the loop that makes the work compound. They are comfortable with ambiguity and long horizons, because the work does not resolve on a quarterly cadence and they have the temperament to keep a team focused through that. And they can tell real capability from sophisticated-sounding noise, which matters enormously in a field where the language of AI is easy to borrow and hard to back up.

They also tend to be unusually good at sequencing. In a domain where experiments are expensive, knowing which question to ask first, and which expensive path not to take, is worth more than raw brilliance. The best research leaders are disciplined about where they spend the organisation's scarce experimental budget, and that discipline is a leadership skill as much as a scientific one.

How to hire for it

Finding these people is not a matter of posting a role and screening applicants. It is a matter of mapping global research and applied-science communities, understanding who is actually doing the work rather than talking about it, and assessing for the rare combination of depth and translation. It means going to the communities where this talent lives, understanding who is genuinely respected by their peers, and being able to evaluate both the science and the systems thinking. And because this talent is scarce everywhere, it usually means operating globally and across borders rather than confining the search to one market.

Build a small senior team, not a single hero

A common and costly instinct is to look for one extraordinary person who embodies both the science and the engineering, a single hire who will solve the whole problem. Those people exist, but they are vanishingly rare, and waiting for one often means hiring nobody for too long, or settling for someone who only looks the part. The more reliable path is to build a small senior nucleus where the capabilities are deliberately paired: a research leader with genuine scientific depth, a leader who can turn research into a shipping product, and the connective tissue of advisors or board members with credibility in the field. Designed well, the team spans the intersection even when no individual does.

This also changes how you attract people. Research-grade talent is drawn to other research-grade talent and to a credible scientific environment far more than to a job description. A respected advisor or a strong first research hire becomes the single best recruiting asset the company has, because it signals to a sceptical community that the work is serious. The order of hiring matters: get the anchor right, and the rest of the team becomes easier to attract, because the people who matter most want to know who else is in the room before they join.

The companies building AI into R&D are making a bet that the hardest problems are the most valuable ones. They are right, but the bet only pays off with leadership built for it. The convenience of hiring a familiar software profile is a false economy in a domain whose entire logic is different. The leadership has to fit the bet, and the bet is on the hard problems.